| pubmed-article:1372622 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C0035870 | lld:lifeskim |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C0679932 | lld:lifeskim |
| pubmed-article:1372622 | lifeskim:mentions | umls-concept:C1510438 | lld:lifeskim |
| pubmed-article:1372622 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1372622 | pubmed:dateCreated | 1992-4-29 | lld:pubmed |
| pubmed-article:1372622 | pubmed:abstractText | Three sets of neutralizing monoclonal antibodies (MAbs) used to type the outer capsid protein VP7 of four group A rotavirus serotypes (1 through 4) were compared in competition immunoassays. Reciprocal competition was observed for each of the VP7 type 2-, 3-, and 4-specific MAbs. The VP7 type 1 MAbs exhibited variable competition patterns with other VP7 type 1 MAbs. MAb RV4:3, which has been used to recognize antigenic variants within VP7 type 1 strains, showed reciprocal competition with the four VP7 type 3 MAbs (RV3:1, YO-1E2, 4F8, and 159) using a VP7 type 3 virus (SA11) as antigen. MAb 2C9, also prepared against VP7 type 1, reacted with VP7 type 3 strains and competed with a VP7 type 3 MAb, 159, using RRV as antigen. Use of the different sets of VP7 type-specific MAbs in the enzyme-linked immunosorbent assay permitted the recognition of six antigenic variants within VP7 types 1, 2, and 3 among specimens whose VP7 type could not be determined previously with only one set of typing MAbs. These results demonstrate differences of typing ability among these VP7-specific MAbs and emphasize the need to improve the sensitivity of typing systems by incorporating panels of MAbs reacting with several neutralizing epitopes. | lld:pubmed |
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| pubmed-article:1372622 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:1372622 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1372622 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1372622 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1372622 | pubmed:issn | 0095-1137 | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:EstesM KMK | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:BishopR FRF | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:TaniguchiKK | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:UrasawaSS | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:GreenbergH... | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:MatsonD ODO | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:CoulsonB SBS | lld:pubmed |
| pubmed-article:1372622 | pubmed:author | pubmed-author:RajPP | lld:pubmed |
| pubmed-article:1372622 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1372622 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:1372622 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1372622 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1372622 | pubmed:pagination | 704-11 | lld:pubmed |
| pubmed-article:1372622 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:1372622 | pubmed:meshHeading | pubmed-meshheading:1372622-... | lld:pubmed |
| pubmed-article:1372622 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1372622 | pubmed:articleTitle | Comparisons of rotavirus VP7-typing monoclonal antibodies by competition binding assay. | lld:pubmed |
| pubmed-article:1372622 | pubmed:affiliation | Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030. | lld:pubmed |
| pubmed-article:1372622 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1372622 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1372622 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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