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pubmed-article:136884pubmed:abstractTextChromosome analyses were made on culture lymphozytes from peripheral blood in 37 patients with humoral and local antibody deficiency syndrome. In one child with humoral IgA-deficiency a ploidymutation of sex chromosomes - a Klinefelter-Syndrome - and a structural variante of chromosome 16 were detected - karyotype 47, XXY, 16q+. No aberrations of chromosomes 18 and 21 were found out in these phenotypic completely normal children. Patients with secret-IgA-deficiency in mucosae had normal karyotypes. Theoretical aspects of possible connection of antibody deficiency syndrome and chromosomal anomalies are discussed.lld:pubmed
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pubmed-article:136884pubmed:pagination167-70lld:pubmed
pubmed-article:136884pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:136884pubmed:year1976lld:pubmed
pubmed-article:136884pubmed:articleTitle[Antibody deficiency syndrome and chromosome aberrations].lld:pubmed
pubmed-article:136884pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:136884pubmed:publicationTypeEnglish Abstractlld:pubmed