Linked Life Data

1359161

Source:http://linkedlifedata.com/resource/pubmed/id/1359161

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pubmed-article:1359161pubmed:abstractTextThe sedative effects of a new alpha 2-adrenoceptor agonist, romifidine, were compared with those of xylazine and detomidine. Five horses were treated with two doses of romifidine (40 micrograms/kg body weight and 80 micrograms/kg body weight), two doses of detomidine (10 micrograms/kg body weight and 20 micrograms/kg body weight) and one dose of xylazine (1 mg/kg body weight) given by intravenous injection using a Latin-square design. The dose of 80 micrograms/kg romifidine appeared equipotent to 1 mg/kg xylazine and 20 micrograms/kg detomidine, although at these doses both xylazine and detomidine had a shorter action. Detomidine 20 micrograms/kg and xylazine both produced greater lowering of the head and a greater degree of ataxia than romifidine at either dose. Romifidine produced sedation similar to that of the other drug regimes. The effect upon imposed stimuli was similar.lld:pubmed
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pubmed-article:1359161pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:1359161pubmed:articleTitleA comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse.lld:pubmed
pubmed-article:1359161pubmed:affiliationDepartment of Surgery and Obstetrics, Royal Veterinary College, University of London, Hatfield, Hertfordshire, UK.lld:pubmed
pubmed-article:1359161pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1359161pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:1359161pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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