| pubmed-article:1347669 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1347669 | lifeskim:mentions | umls-concept:C0026838 | lld:lifeskim |
| pubmed-article:1347669 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:1347669 | lifeskim:mentions | umls-concept:C0076341 | lld:lifeskim |
| pubmed-article:1347669 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:1347669 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1347669 | pubmed:dateCreated | 1992-4-16 | lld:pubmed |
| pubmed-article:1347669 | pubmed:abstractText | This investigation assessed the mechanisms of Tetrazepam action on spasticity using a battery of electromyographic methods. Thirty patients with post-stroke spastic hemiparesis treated with Tetrazepam took part in the investigation. A questionnaire for assessment of subjective improvement after treatment used a 5-point scale. The 5-point scales were used to assess muscle tone, muscle strength and tendon reflexes. A battery of electromyographic methods was used to analyse different mechanisms of spasticity: for alpha-motoneuron activity--the F-wave parameters; for gamma-motoneuron activity--the TA/H amplitude ratio; for presynaptic inhibition--the ratio of H-reflex maximal amplitudes before and after vibration on the Achilles tendon (Hvibr/Hmax); for common interneuron activity--the flexor reflex parameters. Our results revealed that Tetrazepam reduces tone in spastic muscles and has a slight effect on tendon hyperreflexia. It has no influence on muscle strength, Babinski sign and ankle clonus. Tetrazepam acts by decreasing motoneurone activity and increasing presynaptic inhibition. | lld:pubmed |
| pubmed-article:1347669 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1347669 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1347669 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1347669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1347669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1347669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1347669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1347669 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1347669 | pubmed:issn | 0300-9009 | lld:pubmed |
| pubmed-article:1347669 | pubmed:author | pubmed-author:MilanovII | lld:pubmed |
| pubmed-article:1347669 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1347669 | pubmed:volume | 92 | lld:pubmed |
| pubmed-article:1347669 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1347669 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1347669 | pubmed:pagination | 5-15 | lld:pubmed |
| pubmed-article:1347669 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1347669 | pubmed:meshHeading | pubmed-meshheading:1347669-... | lld:pubmed |
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| pubmed-article:1347669 | pubmed:meshHeading | pubmed-meshheading:1347669-... | lld:pubmed |
| pubmed-article:1347669 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1347669 | pubmed:articleTitle | Mechanisms of tetrazepam action on spasticity. | lld:pubmed |
| pubmed-article:1347669 | pubmed:affiliation | Institute of Neurology, Psychiatry & Neurosurgery, IIIrd Neurological clinic, Sofia, Bulgaria. | lld:pubmed |
| pubmed-article:1347669 | pubmed:publicationType | Journal Article | lld:pubmed |
