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pubmed-article:1309380pubmed:abstractTextCamptothecin-11 (CPT-11) is a new semisynthetic derivative of CPT, and has been shown to inhibit DNA topoisomerase I and to have a strong antitumor activity with low toxicity in murine tumors. To evaluate the effectiveness of CPT-11 in patients with non-small-cell lung cancer (NSCLC), a phase II study was conducted between April 1989 and February 1990.lld:pubmed
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pubmed-article:1309380pubmed:articleTitleA phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer.lld:pubmed
pubmed-article:1309380pubmed:affiliationCPT-II Lung Cancer Study Group, Tokyo, Japan.lld:pubmed
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