| pubmed-article:1304212 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C0011777 | lld:lifeskim |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C0071839 | lld:lifeskim |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C0020168 | lld:lifeskim |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C0015399 | lld:lifeskim |
| pubmed-article:1304212 | lifeskim:mentions | umls-concept:C0173022 | lld:lifeskim |
| pubmed-article:1304212 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1304212 | pubmed:dateCreated | 1993-7-6 | lld:pubmed |
| pubmed-article:1304212 | pubmed:abstractText | In a randomized, double-blind clinical trial we studied the protective effect of prednisolone-acetate 1.0% and dexamethasone 0.1% on the blood-aqueous barrier after cataract-extraction and posterior chamber lens implantation. Pre- and postoperative anterior chamber fluorophotometry was performed after i.v. administration of 10% fluorescein-sodium in 20 eyes of 20 patients of whom 16 finished the study (mean age 68.7 +/- 11.0; 13 female, 3 male). The topical application of either drug 5 times daily for 5 days did show a significant difference in surgery mediated disturbance of BAB in each group before and after phacoemulsification. However, when comparing the effect of the two drugs with each other, a difference could not be detected (p = 0.35). To attain a statistical 95% probability that there is no significant difference between the two treatment groups, a number of 690 patients would have had to be investigated. The results can be interpreted as to be due to a better cornea penetration of prednisolone-acetate which compensate the higher glucocorticoid-potency and receptor-affinity of dexamethasone. The untreated fellow-eyes did not reveal a significant difference between the pre- and postoperative anterior chamber fluorescein-concentrations in either treatment group. Anterior chamber fluorophotometry is able to demonstrate the potency and influence of both prednisolone-acetate 1.0% and dexamethasone 0.1% eye-drops on the BAB following phacoemulsification and IOL-implantation. The difference of both drugs does not seem to be of clinical importance in this context. | lld:pubmed |
| pubmed-article:1304212 | pubmed:language | ger | lld:pubmed |
| pubmed-article:1304212 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1304212 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1304212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1304212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1304212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1304212 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1304212 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1304212 | pubmed:issn | 0941-293X | lld:pubmed |
| pubmed-article:1304212 | pubmed:author | pubmed-author:KrieglsteinG... | lld:pubmed |
| pubmed-article:1304212 | pubmed:author | pubmed-author:HilgersR DRD | lld:pubmed |
| pubmed-article:1304212 | pubmed:author | pubmed-author:KonenWW | lld:pubmed |
| pubmed-article:1304212 | pubmed:author | pubmed-author:DiestelhorstM... | lld:pubmed |
| pubmed-article:1304212 | pubmed:author | pubmed-author:AspacherFF | lld:pubmed |
| pubmed-article:1304212 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1304212 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:1304212 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1304212 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1304212 | pubmed:pagination | 342-5 | lld:pubmed |
| pubmed-article:1304212 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:meshHeading | pubmed-meshheading:1304212-... | lld:pubmed |
| pubmed-article:1304212 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1304212 | pubmed:articleTitle | [Effect of 0.1% dexamethasone and 1.0% prednisolone acetate eyedrops on the blood-aqueous humor barrier]. | lld:pubmed |
| pubmed-article:1304212 | pubmed:affiliation | Universitäts-Augenklinik Köln. | lld:pubmed |
| pubmed-article:1304212 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1304212 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:1304212 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1304212 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:1304212 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
