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pubmed-article:12974497pubmed:dateCreated2003-9-16lld:pubmed
pubmed-article:12974497pubmed:abstractTextHuman T-cell Leukaemia Virus Type I (HTLV-I) is a retrovirus that causes Adult T-cell Leukaemia (ATL). The transmission routes of HTLV-I are (i) from infected mothers to their newborn babies, (ii) from infected males (husbands) to females (their wives) by long-term sexual intercourse, and (iii) from infected females (wives) to males (their husbands). Eshima et al. (2001) analysed a continuous-time HTLV-I model with no age structure in the population. In this paper, we consider the population dynamics of HTLV-I infection in a discrete-time mathematical model incorporating an age structure. The necessary and sufficient condition for the extinction of HTLV-I is derived from the mathematical model. A simulation of the HTLV-I infection based on the model demonstrates a rapid reduction of the HTLV-I infection proportion in Japan.lld:pubmed
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pubmed-article:12974497pubmed:authorpubmed-author:EshimaNobuoki...lld:pubmed
pubmed-article:12974497pubmed:authorpubmed-author:TabataMinoruMlld:pubmed
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pubmed-article:12974497pubmed:pagination29-45lld:pubmed
pubmed-article:12974497pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:12974497pubmed:articleTitlePopulation dynamics of HTLV-I infection: a discrete-time mathematical epidemic model approach.lld:pubmed
pubmed-article:12974497pubmed:affiliationDepartment of Biomathematics, Faculty of Medicine, Oita Medical University, Oita 879-5593, Japan. eshima@oita-med.ac.jplld:pubmed
pubmed-article:12974497pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12974497pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed