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pubmed-article:12962567pubmed:dateCreated2003-9-9lld:pubmed
pubmed-article:12962567pubmed:abstractTextTo evaluate the effects of rhG-CSF and rhSCF on mobilization of the peripheral blood stem cells, 15 monkeys were divided into control, rhG-CSF 10 micro g/(kg x day) and rhG-CSF 10 micro g/(kg x day) + rhSCF 50 micro g/(kg x day) treated groups. Monkeys were administered with vehicle, rhG-CSF and rhG-CSF + rhSCF subcutaneously once daily for 14 days, respectively. The results showed that the highest counts of leukocyte of rhG-CSF treated group were 411% of baseline value on day 7 after administration, compared with that of rhG-CSF + rhSCF treated group which were 538% on day 9. The highest counts of leukocytes lasted for 3 days in combined treated group. CFU-GM from peripheral blood in the two groups were 8.37 and 11.75 times higher at 5 and 9 days respectively after the mobilization. It is concluded that rhG-CSF significantly increases the number of peripheral blood leukocytes and CFU-GM, and a better effect can be obtained by rhSCF + rhG-CSF combined administration.lld:pubmed
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pubmed-article:12962567pubmed:authorpubmed-author:HaoJingJlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:WangXin-RuXRlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:XiongGuo-LinG...lld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:LiuXiao-LanXLlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:ZhaoZhen-HuZHlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:GuoDe-HuangDHlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:ZhaoBei-LeiBLlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:ChenSong-SenS...lld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:LuoPeng-YiPYlld:pubmed
pubmed-article:12962567pubmed:authorpubmed-author:LuoQing-Liang...lld:pubmed
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pubmed-article:12962567pubmed:volume11lld:pubmed
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pubmed-article:12962567pubmed:pagination381-4lld:pubmed
pubmed-article:12962567pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:12962567pubmed:year2003lld:pubmed
pubmed-article:12962567pubmed:articleTitle[The effects of rhG-CSF and rhSCF on peripheral blood leukocytes and CFU-GM in rhesus monkeys].lld:pubmed
pubmed-article:12962567pubmed:affiliationInstitute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China.lld:pubmed
pubmed-article:12962567pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12962567pubmed:publicationTypeEnglish Abstractlld:pubmed
pubmed-article:12962567pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed