pubmed-article:12954713 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0024554 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0027883 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0042993 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0450429 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0004927 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
pubmed-article:12954713 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
pubmed-article:12954713 | pubmed:issue | 21 | lld:pubmed |
pubmed-article:12954713 | pubmed:dateCreated | 2003-9-16 | lld:pubmed |
pubmed-article:12954713 | pubmed:abstractText | Caenorhabditis elegans polycystins LOV-1 and PKD-2 are expressed in the male-specific HOB neuron, and are necessary for sensation of the hermaphrodite vulva during mating. We demonstrate that male vulva location behavior and expression of lov-1 and pkd-2 in the ciliated sensory neuron HOB require the activities of transcription factor EGL-46 and to some extent also EGL-44. This EGL-46- regulated program is specific to HOB and is distinct from a general ciliogenic pathway functioning in all ciliated neurons. The ciliogenic pathway regulator DAF-19 affects downstream components of the HOB-specific program indirectly and is independent of EGL-46 activity. The sensory function of HOB requires the combined action of these two distinct regulatory pathways. | lld:pubmed |
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pubmed-article:12954713 | pubmed:language | eng | lld:pubmed |
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pubmed-article:12954713 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:12954713 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12954713 | pubmed:month | Nov | lld:pubmed |
pubmed-article:12954713 | pubmed:issn | 0950-1991 | lld:pubmed |
pubmed-article:12954713 | pubmed:author | pubmed-author:GilJJ | lld:pubmed |
pubmed-article:12954713 | pubmed:author | pubmed-author:SternbergPaul... | lld:pubmed |
pubmed-article:12954713 | pubmed:author | pubmed-author:PretotRene... | lld:pubmed |
pubmed-article:12954713 | pubmed:author | pubmed-author:BurglinThomas... | lld:pubmed |
pubmed-article:12954713 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12954713 | pubmed:volume | 130 | lld:pubmed |
pubmed-article:12954713 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12954713 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12954713 | pubmed:pagination | 5217-27 | lld:pubmed |
pubmed-article:12954713 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:12954713 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12954713 | pubmed:articleTitle | Distinct roles of transcription factors EGL-46 and DAF-19 in specifying the functionality of a polycystin-expressing sensory neuron necessary for C. elegans male vulva location behavior. | lld:pubmed |
pubmed-article:12954713 | pubmed:affiliation | HHMI and Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA. | lld:pubmed |
pubmed-article:12954713 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12954713 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:12954713 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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