Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression.
Source:http://linkedlifedata.com/resource/pubmed/id/12947090
J. Biol. Chem.
2003
Nov
7
278
45
44675-82
