Treating very low birth weight (VLBW) infants with pharmacologic doses of vitamin E as an antioxidant agent has been proposed for preventing or limiting retinopathy of prematurity, intracranial hemorrhage, hemolytic anemia, and chronic lung disease. However, excessive doses of vitamin E may result in side effects.
Pediatrics, Section of Neonatology, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Weiler Hospital Room 725, 1825 Eastchester Road, Bronx, NY 10461, USA.