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pubmed-article:12901585pubmed:abstractTextEpstein-Barr virus infects more than 95% of the human population and is linked to infectious mononucleosis as well as a series of geographically-defined cancers. To date, there is no prophylactic or therapeutic vaccine available for Epstein-Barr virus-associated diseases. New immunotherapeutic approaches, based on cytotoxic T-cells, are being developed depending on the degree of Epstein-Barr virus antigen expression in infected cells. It is hoped that these approaches will provide enough impetus for cytotoxic T-cell-based vaccine development. Approaches for developing vaccines towards the different Epstein-Barr virus-associated diseases are discussed.lld:pubmed
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pubmed-article:12901585pubmed:articleTitleEpstein-Barr virus vaccine: a cytotoxic T-cell-based approach.lld:pubmed
pubmed-article:12901585pubmed:affiliationCCRC.I, Queensland Institute of Medical Research, Royal Brisbane Hospital Post Office, Australia. mandviB@qimer.edu.aulld:pubmed
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