| pubmed-article:12888260 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0009780 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0016786 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0205464 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C1554963 | lld:lifeskim |
| pubmed-article:12888260 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:12888260 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:12888260 | pubmed:dateCreated | 2003-7-30 | lld:pubmed |
| pubmed-article:12888260 | pubmed:abstractText | Fucose is the only component of glycoconjugates of vertebrates in the L-configuration. It exhibits a number of unique and interesting biological properties reviewed briefly in this article. Its constant end-standing position on glycan chains predisposes fucose to play a key role in cell-cell and cell-matrix interactions, mediated by several receptors such as those recognising the Lewis-type blood group substances, fucose-recognising lectines and the mannose-fucose receptors. Some of the as yet unstudied or less well understood properties of L-fucose were explored in the present study, as its non-enzymatic interaction with amine-groups on macromolecules, its cellular uptake attributed to specific transport mechanisms and its effect on fibroblast cell cultures. We could document the stimulation of cell-proliferation and the inhibition of MMP-expression and activation, both for MMP-2 and MMP-9. These and the other shortly reviewed properties of L-fucose may play an important role in its biological applications and actions. | lld:pubmed |
| pubmed-article:12888260 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12888260 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12888260 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12888260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12888260 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12888260 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12888260 | pubmed:issn | 0753-3322 | lld:pubmed |
| pubmed-article:12888260 | pubmed:author | pubmed-author:RobertLL | lld:pubmed |
| pubmed-article:12888260 | pubmed:author | pubmed-author:RobertA MAM | lld:pubmed |
| pubmed-article:12888260 | pubmed:author | pubmed-author:PéterszegiGG | lld:pubmed |
| pubmed-article:12888260 | pubmed:author | pubmed-author:Fodil-Bourahl... | lld:pubmed |
| pubmed-article:12888260 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12888260 | pubmed:volume | 57 | lld:pubmed |
| pubmed-article:12888260 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12888260 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12888260 | pubmed:pagination | 240-5 | lld:pubmed |
| pubmed-article:12888260 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:meshHeading | pubmed-meshheading:12888260... | lld:pubmed |
| pubmed-article:12888260 | pubmed:articleTitle | Pharmacological properties of fucose. Applications in age-related modifications of connective tissues. | lld:pubmed |
| pubmed-article:12888260 | pubmed:affiliation | Laboratoire Universitaire de Recherche en Ophtalmologie, Faculté de Médecine Broussais-Hôtel Dieu, Université Pierre et Marie Curie (Paris 6), 1, place du Parvis-Notre-Dame, 75181 Paris cedex 4, France. | lld:pubmed |
| pubmed-article:12888260 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12888260 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
