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pubmed-article:12860493pubmed:abstractTextBecause traditional therapies for rheumatoid arthritis (RA) such as methotrexate (MTX) do not produce an adequate response in many patients, newer therapies that block the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) are increasingly being used in combination with MTX.lld:pubmed
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pubmed-article:12860493pubmed:articleTitleEfficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumor necrosis factor-alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study.lld:pubmed
pubmed-article:12860493pubmed:affiliationCedars-Sinai Medical Center, Los Angeles, California 90048, USA. weisman@cshs.orglld:pubmed
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