| pubmed-article:12858410 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C1179149 | lld:lifeskim |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C0037285 | lld:lifeskim |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C0699748 | lld:lifeskim |
| pubmed-article:12858410 | lifeskim:mentions | umls-concept:C0854530 | lld:lifeskim |
| pubmed-article:12858410 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:12858410 | pubmed:dateCreated | 2003-7-14 | lld:pubmed |
| pubmed-article:12858410 | pubmed:abstractText | In order to elucidate the pathogenesis of variant B human herpesvirus 6 (HHV-6) infection in skin tissues, an A431 cell line was inoculated with variant B HHV-6. HHV-6 causes abortive infection in the A431 cells, because neither late antigen (OHV-3 antigen) nor progeny virus is produced. Maximum levels of HHV-6 antigen (IEA/ex3 antigen)-positive cells (36.4%) were observed 48 hr after viral infection. Cocultivation of HHV-6-infected cord blood mononuclear cells with A431 cells was necessary for the establishment of a sufficient level of viral infection. Cell-to-cell contact between the infected cord blood mononuclear cells and A431 cells was crucial for increasing infection efficiency. To determine the biological effect of HHV-6 infection, flow cytometric analysis was carried out in HHV-6- and mock-infected A431 cells. Although no alteration was observed in VCAM-1 and ELAM-1 expression, that of HLA-ABC, HLA-DR, and ICAM-1 was upregulated after infection with HHV-6. | lld:pubmed |
| pubmed-article:12858410 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12858410 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12858410 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12858410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12858410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12858410 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12858410 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:12858410 | pubmed:issn | 0146-6615 | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:YoshikawaTets... | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:AsanoYoshizoY | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:NishiyamaYuki... | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:KurataTakeshi... | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:IwasakiTakuya... | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:AkimotoShihoS | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:OzakiTakaoT | lld:pubmed |
| pubmed-article:12858410 | pubmed:author | pubmed-author:GoshimaFumiF | lld:pubmed |
| pubmed-article:12858410 | pubmed:copyrightInfo | Copyright 2003 Wiley-Liss, Inc. | lld:pubmed |
| pubmed-article:12858410 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12858410 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:12858410 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12858410 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12858410 | pubmed:pagination | 62-8 | lld:pubmed |
| pubmed-article:12858410 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:meshHeading | pubmed-meshheading:12858410... | lld:pubmed |
| pubmed-article:12858410 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12858410 | pubmed:articleTitle | Human herpesvirus 6 infection of human epidermal cell line: pathogenesis of skin manifestations. | lld:pubmed |
| pubmed-article:12858410 | pubmed:affiliation | Laboratory of Virology, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Aichi, Japan. tetsushi@fujita-hu.ac.jp | lld:pubmed |
| pubmed-article:12858410 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12858410 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
