| pubmed-article:12819322 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C0085756 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C0020538 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C0022658 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C0038215 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C1879746 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C1547011 | lld:lifeskim |
| pubmed-article:12819322 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:12819322 | pubmed:issue | 7 Suppl 2 | lld:pubmed |
| pubmed-article:12819322 | pubmed:dateCreated | 2003-6-23 | lld:pubmed |
| pubmed-article:12819322 | pubmed:abstractText | The African American Study of Kidney Disease and Hypertension (AASK) is a multicenter randomized clinical trial designed to test the effectiveness of three anti-hypertensive drug regimens and two levels of BP control on the progression of hypertensive kidney disease. Participants include African-American men and women aged 18 to 70 yr who have hypertensive kidney disease and GFR between 20 and 65 ml/min per 1.73 m(2). The three anti-hypertensive drug regimens include an angiotensin converting enzyme inhibitor (ramipril), a dihydropyridine calcium channel blocker (amlodipine) or a beta-blocker (metoprolol) as initial therapy. The BP control levels are a lower goal (mean arterial pressure, </=92 mmHg) and a usual goal (mean arterial pressure, 102 to 107 mmHg inclusive). The primary outcome is rate of change in renal function as measured by GFR, assessed by (125) I-iothalamate clearance. The main secondary patient outcome is a composite including the following events: (1) reduction in GFR by 50%, (2) end-stage renal disease, or (3) death. | lld:pubmed |
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| pubmed-article:12819322 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12819322 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12819322 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12819322 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12819322 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12819322 | pubmed:issn | 1046-6673 | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:GassmanJennif... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:BakrisGeorgeG | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:WrightJackson... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:WangShin-RuSR | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:AgodoaLawrenc... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:LewisJuliaJ | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:GreeneTomT | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:RandallOtelio... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:BeckGerald... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:DouglasJanice... | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:JamersonKenK | lld:pubmed |
| pubmed-article:12819322 | pubmed:author | pubmed-author:KutnerMichael... | lld:pubmed |
| pubmed-article:12819322 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12819322 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:12819322 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12819322 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12819322 | pubmed:pagination | S154-65 | lld:pubmed |
| pubmed-article:12819322 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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