| pubmed-article:1279946 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0220847 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0017278 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0341439 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C1422036 | lld:lifeskim |
| pubmed-article:1279946 | lifeskim:mentions | umls-concept:C0005863 | lld:lifeskim |
| pubmed-article:1279946 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:1279946 | pubmed:dateCreated | 1992-12-18 | lld:pubmed |
| pubmed-article:1279946 | pubmed:abstractText | We detected an antibody to HCV envelope protein (E1) in sera of patients with HCV-related chronic liver diseases (20 patients with chronic hepatitis and 5 patients with liver cirrhosis) by Western blotting using the fusion protein of E1 envelope protein and beta-galactosidase as an antigen. The antibody to HCV E1 (anti-HCV E1) was detected in 8 (42%) of 19 patients positive for HCV-RNA (16 were positive and 3 were negative for antibody to C100-3) and in 1 (17%) of 6 patients negative for HCV-RNA but positive for antibody to C100-3. HCV-RNA was detected in 8 (89%) of 9 anti-HCV E1 positive sera. The value of alanine aminotransferase was significantly higher in patients positive for anti-HCV E1 than in patients negative for the antibody. Although an antibody to the envelope protein of HCV is suspected to be one of the candidates of virus-neutralizing antibodies, our results suggest this hypothesis appears to be unlikely. | lld:pubmed |
| pubmed-article:1279946 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1279946 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1279946 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1279946 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1279946 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1279946 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1279946 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1279946 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1279946 | pubmed:issn | 0386-300X | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:KoideNN | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:SakaguchiKK | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:OkaTT | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:TsujiTT | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:SasakiSS | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:HanafusaTT | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:YumotoYY | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:TakayamaNN | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:HadaHH | lld:pubmed |
| pubmed-article:1279946 | pubmed:author | pubmed-author:ShinjiTT | lld:pubmed |
| pubmed-article:1279946 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1279946 | pubmed:volume | 46 | lld:pubmed |
| pubmed-article:1279946 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1279946 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1279946 | pubmed:pagination | 365-70 | lld:pubmed |
| pubmed-article:1279946 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:meshHeading | pubmed-meshheading:1279946-... | lld:pubmed |
| pubmed-article:1279946 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1279946 | pubmed:articleTitle | Detection by western blotting of an antibody to the hepatitis C virus E1 envelope protein in sera of patients with chronic liver disease. | lld:pubmed |
| pubmed-article:1279946 | pubmed:affiliation | First Department of Internal Medicine, Okayama University Medical School, Japan. | lld:pubmed |
| pubmed-article:1279946 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1279946 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
