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pubmed-article:12788774pubmed:abstractTextMoraxella osloensis is a bacterium that is mutualistically associated with Phasmarhabditis hermaphrodita, a nematode that has potential for the biocontrol of mollusk pests, especially the slug Deroceras reticulatum. We discovered that purified M. osloensis lipopolysaccharide (LPS) possesses a lethal toxicity to D. reticulatum when administered by injection but no contact or oral toxicity to this slug. The toxicity of the LPS resides in the lipid A moiety. M. osloensis LPS was semiquantitated at 6 x 10(7) endotoxin units per mg. The LPS is a rough-type LPS with an estimated molecular weight of 5,300. Coinjection of galactosamine with the LPS increased the LPS's toxicity to the slug two- to four-fold. The galactosamine-induced sensitization of the slug to the LPS was reversed completely by uridine.lld:pubmed
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pubmed-article:12788774pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:12788774pubmed:year2003lld:pubmed
pubmed-article:12788774pubmed:articleTitleCharacterization of the first molluscicidal lipopolysaccharide from Moraxella osloensis.lld:pubmed
pubmed-article:12788774pubmed:affiliationDepartment of Entomology, Ohio Agricultural Research and Development Center, Ohio State University, Wooster, Ohio 44691, USA.lld:pubmed
pubmed-article:12788774pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12788774pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed