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pubmed-article:12763851pubmed:abstractTextThe sorting and regulation of the Na,K and H,K-ATPases requires that the pump proteins must associate, at least transiently, with kinases, phosphatases, scaffolding molecules, and components of the cellular trafficking machinery. The identities of these interacting proteins and the nature of their associations with the pump polypeptides have yet to be elucidated. We have begun a series of yeast two-hybrid screens employing structurally defined segments of pump polypeptides as baits in order to gain insight into the nature and function of these interacting proteins.lld:pubmed
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pubmed-article:12763851pubmed:articleTitleIon pump-interacting proteins: promising new partners.lld:pubmed
pubmed-article:12763851pubmed:affiliationDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.lld:pubmed
pubmed-article:12763851pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12763851pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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