| pubmed-article:12749731 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:12749731 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:12749731 | lifeskim:mentions | umls-concept:C0170657 | lld:lifeskim |
| pubmed-article:12749731 | lifeskim:mentions | umls-concept:C0017270 | lld:lifeskim |
| pubmed-article:12749731 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:12749731 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:12749731 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:12749731 | pubmed:dateCreated | 2003-5-16 | lld:pubmed |
| pubmed-article:12749731 | pubmed:abstractText | Americans of African ancestry are less likely to receive a selective serotonin reuptake inhibitor (SSRI) for treatment of major depressive disorder than Americans of European ancestry. A functional insertion/deletion polymorphism in the promoter of the serotonin transporter (5-HTT) gene SLC6A4 has been shown to modulate SLC6A4 transcription, affecting response to SSRIs. Several studies in populations of predominantly European ancestry have consistently found that the SLC6A4 promoter polymorphism (referred to as the 5-HTT-linked polymorphic region; 5-HTTLPR) long (L) allele is associated with better response to SSRI treatment than the short (S) allele. | lld:pubmed |
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| pubmed-article:12749731 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12749731 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12749731 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12749731 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12749731 | pubmed:issn | 1175-2203 | lld:pubmed |
| pubmed-article:12749731 | pubmed:author | pubmed-author:FerrellRobert... | lld:pubmed |
| pubmed-article:12749731 | pubmed:author | pubmed-author:PollockBruce... | lld:pubmed |
| pubmed-article:12749731 | pubmed:author | pubmed-author:LotrichFranci... | lld:pubmed |
| pubmed-article:12749731 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12749731 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:12749731 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12749731 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12749731 | pubmed:pagination | 145-7 | lld:pubmed |
| pubmed-article:12749731 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:12749731 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12749731 | pubmed:articleTitle | Serotonin transporter promoter polymorphism in African Americans : allele frequencies and implications for treatment. | lld:pubmed |
| pubmed-article:12749731 | pubmed:affiliation | Department of Psychiatry, Western Psychiatric Institute and Clinics, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA. lotrichfe@msx.upmc.edu | lld:pubmed |
| pubmed-article:12749731 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12749731 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12749731 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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