| pubmed-article:12743313 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12743313 | lifeskim:mentions | umls-concept:C0014080 | lld:lifeskim |
| pubmed-article:12743313 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:12743313 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:12743313 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:12743313 | pubmed:dateCreated | 2003-5-13 | lld:pubmed |
| pubmed-article:12743313 | pubmed:abstractText | We developed a system for complete replication of encephalomyocarditis virus (EMCV) in a test tube by using an in vitro translation extract from Krebs-2 cells. Efficient virus synthesis occurred in a narrow range of Mg(2+) and EMCV RNA concentrations. Excess input RNA impaired RNA replication and virus production but not translation. This suggests the existence of a negative-feedback mechanism for regulation of RNA replication by the viral plus-strand RNA or proteins. | lld:pubmed |
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| pubmed-article:12743313 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:12743313 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12743313 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12743313 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:12743313 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:12743313 | pubmed:author | pubmed-author:SonenbergNahu... | lld:pubmed |
| pubmed-article:12743313 | pubmed:author | pubmed-author:SvitkinYuri... | lld:pubmed |
| pubmed-article:12743313 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12743313 | pubmed:volume | 77 | lld:pubmed |
| pubmed-article:12743313 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12743313 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12743313 | pubmed:pagination | 6551-5 | lld:pubmed |
| pubmed-article:12743313 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:12743313 | pubmed:meshHeading | pubmed-meshheading:12743313... | lld:pubmed |
| pubmed-article:12743313 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12743313 | pubmed:articleTitle | Cell-free synthesis of encephalomyocarditis virus. | lld:pubmed |
| pubmed-article:12743313 | pubmed:affiliation | Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada H3G 1Y6. yuri.svitkine@mcgill.ca | lld:pubmed |
| pubmed-article:12743313 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12743313 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:12743313 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
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