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pubmed-article:12697854pubmed:abstractTextTumor-infiltrating macrophages secrete cytokines, including Fas ligand, tumor necrosis factor-alpha (TNF-alpha), and TNF-related apoptosis-inducing ligand (TRAIL). TRAIL induces apoptosis in tumor cells but not in normal cells; however, regulation of TRAIL and its receptors in cancer patients is relatively uncharacterized. We investigated whether macrophages from cancer patients produce TRAIL and whether apoptosis in cultured colon adenocarcinoma cells involves TRAIL and its receptors.lld:pubmed
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pubmed-article:12697854pubmed:articleTitleMacrophages from cancer patients: analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis.lld:pubmed
pubmed-article:12697854pubmed:affiliationGroupe Immunité des Muqueuses et Agents Pathogénes [GIMAP]), Jean Monnet University, Saint-Etienne, France.lld:pubmed
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