| pubmed-article:12687299 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12687299 | lifeskim:mentions | umls-concept:C0085470 | lld:lifeskim |
| pubmed-article:12687299 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
| pubmed-article:12687299 | lifeskim:mentions | umls-concept:C0005100 | lld:lifeskim |
| pubmed-article:12687299 | lifeskim:mentions | umls-concept:C0054858 | lld:lifeskim |
| pubmed-article:12687299 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:12687299 | pubmed:dateCreated | 2003-11-3 | lld:pubmed |
| pubmed-article:12687299 | pubmed:abstractText | Pseudomonas putida CSV86 metabolizes 1- and 2-methylnaphthalene through distinct catabolic and detoxification pathways. In spite of the similarity in the steps involved in the methylnaphthalene detoxification and the toluene side-chain hydroxylation pathways, the strain failed to utilize toluene or xylenes. However, it could grow on benzyl alcohol, 2- and 4-hydroxybenzyl alcohol. Metabolic studies suggest that the benzyl alcohol metabolism proceeds via the benzaldehyde, benzoate, and catechol ortho-cleavage pathway, in contrast to the well established catechol meta-cleavage pathway. Carbon source-dependent enzyme activity studies suggest that the degradation of aromatic alcohol involves two regulons. Aromatic alcohol induces the upper regulon, which codes for aromatic alcohol- and aromatic aldehyde-dehydrogenase and converts alcohol into acid. The aromatic acid so generated induces the specific lower regulon and is metabolized via either the ortho- or the meta-cleavage pathway. CSV86 cells transform 1- and 2-methylnaphthalene to 1- and 2-hydroxymethyl naphthalene, which are further converted to the respective naphthoic acids due to the basal level expression and broad substrate specificity of the upper regulon enzymes. | lld:pubmed |
| pubmed-article:12687299 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12687299 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12687299 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12687299 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12687299 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12687299 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12687299 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12687299 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12687299 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12687299 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12687299 | pubmed:issn | 0175-7598 | lld:pubmed |
| pubmed-article:12687299 | pubmed:author | pubmed-author:BasuAA | lld:pubmed |
| pubmed-article:12687299 | pubmed:author | pubmed-author:PhaleP SPS | lld:pubmed |
| pubmed-article:12687299 | pubmed:author | pubmed-author:DixitS SSS | lld:pubmed |
| pubmed-article:12687299 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12687299 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:12687299 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12687299 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12687299 | pubmed:pagination | 579-85 | lld:pubmed |
| pubmed-article:12687299 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12687299 | pubmed:meshHeading | pubmed-meshheading:12687299... | lld:pubmed |
| pubmed-article:12687299 | pubmed:meshHeading | pubmed-meshheading:12687299... | lld:pubmed |
| pubmed-article:12687299 | pubmed:meshHeading | pubmed-meshheading:12687299... | lld:pubmed |
| pubmed-article:12687299 | pubmed:meshHeading | pubmed-meshheading:12687299... | lld:pubmed |
| pubmed-article:12687299 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12687299 | pubmed:articleTitle | Metabolism of benzyl alcohol via catechol ortho-pathway in methylnaphthalene-degrading Pseudomonas putida CSV86. | lld:pubmed |
| pubmed-article:12687299 | pubmed:affiliation | Biotechnology Group, School of Biosciences and Bioengineering, Indian Institute of Technology, 400 076 Bombay, Mumbai, India. | lld:pubmed |
| pubmed-article:12687299 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12687299 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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