Cartilage swelling is an early event in osteoarthritis (OA). However, the response of chondrocytes to increased tissue hydration is unknown. This work studied the volume and morphology of living in situ human chondrocytes as a function of cartilage degeneration.
Division of Clinical and Laboratory Sciences, Department of Biomedical Sciences (Physiology), University Medical School, University of Edinburgh, Scotland, Edinburgh, UK.