| pubmed-article:12676124 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0870134 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0005953 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0229664 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:12676124 | lifeskim:mentions | umls-concept:C0079411 | lld:lifeskim |
| pubmed-article:12676124 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12676124 | pubmed:dateCreated | 2003-4-4 | lld:pubmed |
| pubmed-article:12676124 | pubmed:abstractText | We examined whether bovine monocyte-derived and bone marrow (BM) dendritic cells (DCs) regulate antibody production in activated peripheral blood B cells. DCs were generated from monocytes and BM progenitors in the presence of bovine recombinant granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4). Monocyte-derived DCs promoted B cells activated by the anti-CD3 triggered CD4(+) T cells or through immunoglobulin M (IgM) receptor to increase the level of IgG secretion. Furthermore, the addition of DCs triggered B cells activated through IgM receptors to produce IgG2 and IgA, thus inducing an isotype switch. BM-derived DCs increased the production of IgG in B cells activated by the anti-CD3 triggered CD4(+) T cells, but unlike monocyte-derived DCs did not have any effect on B cells activated through surface IgM. These data suggest that the regulation of humoral immune responses in cattle depends on the origin of DCs and the mode of B cell activation. | lld:pubmed |
| pubmed-article:12676124 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12676124 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12676124 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12676124 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12676124 | pubmed:issn | 0147-9571 | lld:pubmed |
| pubmed-article:12676124 | pubmed:author | pubmed-author:PinchukL MLM | lld:pubmed |
| pubmed-article:12676124 | pubmed:author | pubmed-author:RoditiII | lld:pubmed |
| pubmed-article:12676124 | pubmed:author | pubmed-author:KrugerE FEF | lld:pubmed |
| pubmed-article:12676124 | pubmed:author | pubmed-author:FurgerAA | lld:pubmed |
| pubmed-article:12676124 | pubmed:author | pubmed-author:BoydB LBL | lld:pubmed |
| pubmed-article:12676124 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12676124 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:12676124 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12676124 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12676124 | pubmed:pagination | 233-49 | lld:pubmed |
| pubmed-article:12676124 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
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| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:meshHeading | pubmed-meshheading:12676124... | lld:pubmed |
| pubmed-article:12676124 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12676124 | pubmed:articleTitle | Bovine dendritic cells generated from monocytes and bone marrow progenitors regulate immunoglobulin production in peripheral blood B cells. | lld:pubmed |
| pubmed-article:12676124 | pubmed:affiliation | Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, P.O. Box 6100, 39762-6100, Mississippi State, MS, USA. pinchuk@cvm.msstate.edu | lld:pubmed |
| pubmed-article:12676124 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12676124 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12676124 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12676124 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12676124 | lld:pubmed |
