| pubmed-article:12672056 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C1155008 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C2266866 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:12672056 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:12672056 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12672056 | pubmed:dateCreated | 2003-4-2 | lld:pubmed |
| pubmed-article:12672056 | pubmed:abstractText | We report here a role for cyclic AMP-responsive element-binding protein-1 (CREB-1) in B cell antigen receptor (BCR)-induced growth inhibition by IFN-gamma. BCR-induced proliferation is negatively regulated by IFN-gamma. Stimulation through BCR resulted in dose-dependent induction of CREB-1 binding to the consensus cyclic AMP-responsive element. Recombinant IFN-gamma inhibited the BCR-induced CREB-1 DNA binding activity and cell proliferation in B cells from signal transducer and activator of transcription-1 (STAT-1)(+/+), but not STAT-1(-/-) mice. These studies provide the first evidence for cross-talk between the STAT-1 and CREB-1 signaling pathways in IFN-gamma-mediated negative regulation of B cell activation. | lld:pubmed |
| pubmed-article:12672056 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12672056 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672056 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12672056 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12672056 | pubmed:issn | 0014-2980 | lld:pubmed |
| pubmed-article:12672056 | pubmed:author | pubmed-author:BondadaSubbar... | lld:pubmed |
| pubmed-article:12672056 | pubmed:author | pubmed-author:MuthusamyNata... | lld:pubmed |
| pubmed-article:12672056 | pubmed:author | pubmed-author:FrissoraFrank... | lld:pubmed |
| pubmed-article:12672056 | pubmed:author | pubmed-author:ChenHui-ChenH... | lld:pubmed |
| pubmed-article:12672056 | pubmed:author | pubmed-author:DurbinJoanJ | lld:pubmed |
| pubmed-article:12672056 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12672056 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:12672056 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12672056 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12672056 | pubmed:pagination | 907-12 | lld:pubmed |
| pubmed-article:12672056 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
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| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:meshHeading | pubmed-meshheading:12672056... | lld:pubmed |
| pubmed-article:12672056 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12672056 | pubmed:articleTitle | IFN-gamma-mediated inhibition of antigen receptor-induced B cell proliferation and CREB-1 binding activity requires STAT-1 transcription factor. | lld:pubmed |
| pubmed-article:12672056 | pubmed:affiliation | Children's Research Institute, Wexner Institute for Pediatric Research, Columbus, OH 43205, USA. | lld:pubmed |
| pubmed-article:12672056 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12672056 | lld:pubmed |
