pubmed-article:126428 | pubmed:abstractText | The technique of bone marrow cultures in vitro on semi solid agar medium has been applied to the study of 24 cases of chronic myeloid leukemia in chronic phase and/or in acute blastic crisis. At the chronic phase of the disease the colony forming capacity is normal or above the normal range. In blastic crisis the number of colonies is very low. In the same time clusters are prominent. | lld:pubmed |