| pubmed-article:12642101 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12642101 | lifeskim:mentions | umls-concept:C0206267 | lld:lifeskim |
| pubmed-article:12642101 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:12642101 | lifeskim:mentions | umls-concept:C0282629 | lld:lifeskim |
| pubmed-article:12642101 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:12642101 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:12642101 | pubmed:dateCreated | 2003-3-18 | lld:pubmed |
| pubmed-article:12642101 | pubmed:abstractText | The X-ray crystal structure of Cowpea chlorotic mottle bromovirus (CCMV) revealed a unique tubular structure formed by the interaction of the N-termini from six coat protein subunits at each three-fold axis of the assembled virion. This structure, termed the beta-hexamer, consists of six short beta-strands. The beta-hexamer was postulated to play a critical role in the assembly and stability of the virion by stabilizing hexameric capsomers. Mutational analyses of the beta-hexamer structure, utilizing both in vitro and in vivo assembly assays, demonstrate that this structure is not required for virion formation devoid of nucleic acids in vitro or for RNA-containing virions in vivo. However, the beta-hexamer structure does contribute to virion stability in vitro and modulates disease expression in vivo. These results support a model for CCMV assembly through pentamer intermediates. | lld:pubmed |
| pubmed-article:12642101 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12642101 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12642101 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12642101 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12642101 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12642101 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12642101 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:12642101 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:JohnsonJ EJE | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:BakerT STS | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:DouglasTT | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:YoungM JMJ | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:ZlotnickAA | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:ZhaoXX | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:OlsonNN | lld:pubmed |
| pubmed-article:12642101 | pubmed:author | pubmed-author:WillitsDD | lld:pubmed |
| pubmed-article:12642101 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12642101 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:12642101 | pubmed:volume | 306 | lld:pubmed |
| pubmed-article:12642101 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12642101 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12642101 | pubmed:pagination | 280-8 | lld:pubmed |
| pubmed-article:12642101 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:12642101 | pubmed:meshHeading | pubmed-meshheading:12642101... | lld:pubmed |
| pubmed-article:12642101 | pubmed:meshHeading | pubmed-meshheading:12642101... | lld:pubmed |
| pubmed-article:12642101 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12642101 | pubmed:articleTitle | Effects of the cowpea chlorotic mottle bromovirus beta-hexamer structure on virion assembly. | lld:pubmed |
| pubmed-article:12642101 | pubmed:affiliation | Department of Plant Sciences Plant Pathology, Montana State University, Bozeman, MT 59717, USA. | lld:pubmed |
| pubmed-article:12642101 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12642101 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12642101 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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