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pubmed-article:12626463pubmed:abstractTextMixed connective tissue disease is an overlap syndrome characterized by features of different systemic autoimmune diseases and a high titer of U1-snRNP antibodies. We examine here the autoantibodies to nucleoporin p62 in a severe case of mixed connective tissue disease in a young male patient. Thus far, p62 antibodies have mainly been described in cases of primary biliary cirrhosis. We speculate that the presence of p62 antibodies is an indication of a poor prognosis in connective tissue disorders.lld:pubmed
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pubmed-article:12626463pubmed:authorpubmed-author:KneitzChristi...lld:pubmed
pubmed-article:12626463pubmed:authorpubmed-author:TonyHans-Pete...lld:pubmed
pubmed-article:12626463pubmed:authorpubmed-author:KraemerDoris...lld:pubmed
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pubmed-article:12626463pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:12626463pubmed:articleTitleNucleoporin p62 antibodies in a case of mixed connective tissue disease.lld:pubmed
pubmed-article:12626463pubmed:affiliationMedizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany. d.kraemer@medizin.uni-wuerzburg.delld:pubmed
pubmed-article:12626463pubmed:publicationTypeJournal Articlelld:pubmed
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