There is increasing evidence that mitochondrial DNA (mtDNA) anomalies in sperm may lead to infertility. Point mutations, deletions and the presence of a specific mtDNA haplogroup have been associated with poor sperm quality, but little attention has been paid to the role of mtDNA content.
INSERM EMI-U 00-18, Laboratoire de Biochimie et Biologie Moléculaire, Laboratoire d'Histologie-Embryologie-Cytologie, UF de Biologie de la Reproduction, CHU d'Angers, F-49033 Angers, France.
