| pubmed-article:12615427 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12615427 | lifeskim:mentions | umls-concept:C0040558 | lld:lifeskim |
| pubmed-article:12615427 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:12615427 | lifeskim:mentions | umls-concept:C0376613 | lld:lifeskim |
| pubmed-article:12615427 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:12615427 | lifeskim:mentions | umls-concept:C0678420 | lld:lifeskim |
| pubmed-article:12615427 | pubmed:issue | 13-14 | lld:pubmed |
| pubmed-article:12615427 | pubmed:dateCreated | 2003-3-4 | lld:pubmed |
| pubmed-article:12615427 | pubmed:abstractText | BALB/c mice were intramuscularly immunized with low doses (25-50microg) of DNA cocktail containing plasmids encoding the full-length SAG1/P30 and the 196-561 terminal sequence of ROP2 genes. This immunization resulted in a Th1-type response with predominance of IgG2a and a specific T-cell proliferation with high levels of interferon-gamma (IFN-gamma) secretion, whereas no IL-4 was detected. Moreover, DNA cocktail immunization induced a long-lasting protection against a lethal challenge with the highly virulent Toxoplasma gondii RH strain, whereas low doses of single genes were not protective. These results support further investigations to achieve a multigene anti-T. gondii DNA vaccine. | lld:pubmed |
| pubmed-article:12615427 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12615427 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12615427 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12615427 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12615427 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12615427 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12615427 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12615427 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:12615427 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:AngelSergio... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:Lannes-Vieira... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:FachadoAlbert... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:RodriguezAlex... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:PintoDiamar... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:VilaIvianeI | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:AcostaArmando... | lld:pubmed |
| pubmed-article:12615427 | pubmed:author | pubmed-author:AmendoeiraReg... | lld:pubmed |
| pubmed-article:12615427 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12615427 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:12615427 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:12615427 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12615427 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12615427 | pubmed:pagination | 1327-35 | lld:pubmed |
| pubmed-article:12615427 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:meshHeading | pubmed-meshheading:12615427... | lld:pubmed |
| pubmed-article:12615427 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12615427 | pubmed:articleTitle | Protective effect of a naked DNA vaccine cocktail against lethal toxoplasmosis in mice. | lld:pubmed |
| pubmed-article:12615427 | pubmed:affiliation | Laboratory of Autoimmunity and Immunoregulation, Department of Immunology, Oswaldo Cruz Institute, Fiocruz. Av Brasil, 4365, Rio de Janeiro 21045-900, Brazil. | lld:pubmed |
| pubmed-article:12615427 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12615427 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12615427 | lld:pubmed |
