Linked Life Data

12605459

Source:http://linkedlifedata.com/resource/pubmed/id/12605459

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:12605459rdf:typepubmed:Citationlld:pubmed
pubmed-article:12605459lifeskim:mentionsumls-concept:C0024554lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0006104lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0221205lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0010226lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0205307lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0079429lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C1823902lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C0013139lld:lifeskim
pubmed-article:12605459lifeskim:mentionsumls-concept:C1551336lld:lifeskim
pubmed-article:12605459pubmed:issue1lld:pubmed
pubmed-article:12605459pubmed:dateCreated2003-2-26lld:pubmed
pubmed-article:12605459pubmed:abstractTextThe fruitless (fru) gene is a member of the Drosophila melanogaster somatic sex determination genetic pathway. Although it has been hypothesized that the primary function of fru is to regulate a genetic hierarchy specifying development of adult male courtship behavior, genes acting downstream of fru have not yet been identified. Here we demonstrate that the yellow (y) gene is genetically downstream of fru in the 3(rd)-instar larval brain. Yellow protein is present at elevated levels in neuroblasts, which also show expression of male-specific FRU proteins, compared to control neuroblasts without FRU. A location for y downstream of fru in a genetic pathway was experimentally demonstrated by analysis of fru mutants lacking transcription of zinc-finger DNA binding domains, and of animals with temporal, spatial, or sexual mis-expression of male-specific FRU. A subset of fru and y mutants is known to reduce levels of a specific behavioral component of the male courtship ritual, wing extension, and FRU and Yellow were detected in the general region of the brain whose maleness is necessary for development of that behavior. We therefore hypothesized that ectopic expression of Yellow in the 3(rd)-instar brain, in a y null background, would rescue low levels of wing extension and male competitive mating success, and this was found to be the case. Overall, these data suggest that y is a downstream member of the fru branch of the D. melanogaster sex determination hierarchy, where it plays a currently unknown role in the development of adult male wing extension during courtship.lld:pubmed
pubmed-article:12605459pubmed:languageenglld:pubmed
pubmed-article:12605459pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:citationSubsetIMlld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:12605459pubmed:statusMEDLINElld:pubmed
pubmed-article:12605459pubmed:monthAprlld:pubmed
pubmed-article:12605459pubmed:issn0022-3034lld:pubmed
pubmed-article:12605459pubmed:authorpubmed-author:LongAnthony...lld:pubmed
pubmed-article:12605459pubmed:authorpubmed-author:WittkoppPatri...lld:pubmed
pubmed-article:12605459pubmed:authorpubmed-author:RadovicAnnaAlld:pubmed
pubmed-article:12605459pubmed:authorpubmed-author:DrapeauMark...lld:pubmed
pubmed-article:12605459pubmed:copyrightInfoCopyright 2003 Wiley Periodicals, Inc. J Neurobiol 55: 53-72, 2003lld:pubmed
pubmed-article:12605459pubmed:issnTypePrintlld:pubmed
pubmed-article:12605459pubmed:volume55lld:pubmed
pubmed-article:12605459pubmed:ownerNLMlld:pubmed
pubmed-article:12605459pubmed:authorsCompleteYlld:pubmed
pubmed-article:12605459pubmed:pagination53-72lld:pubmed
pubmed-article:12605459pubmed:dateRevised2008-10-15lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:meshHeadingpubmed-meshheading:12605459...lld:pubmed
pubmed-article:12605459pubmed:year2003lld:pubmed
pubmed-article:12605459pubmed:articleTitleA gene necessary for normal male courtship, yellow, acts downstream of fruitless in the Drosophila melanogaster larval brain.lld:pubmed
pubmed-article:12605459pubmed:affiliationDepartment of Ecology and Evolutionary Biology, University of California - Irvine, Irvine, California 92697, USA. drapeau@darwin.bio.uci.edulld:pubmed
pubmed-article:12605459pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12605459pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:12605459pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:12605459pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:30980entrezgene:pubmedpubmed-article:12605459lld:entrezgene
entrez-gene:32083entrezgene:pubmedpubmed-article:12605459lld:entrezgene
entrez-gene:42226entrezgene:pubmedpubmed-article:12605459lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:12605459lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:12605459lld:pubmed