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pubmed-article:12601106pubmed:abstractTextOne of the diagnostic imaging hallmarks of MS is the uptake of IV administered contrast material in new lesions in the brain, signaling blood-brain barrier breakdown and active inflammation. Many clinical drug trials are designed based on the assumption that lesion enhancement on MRI remains visible on average for 1 month. For practical reasons, few serial MRI studies of patients with MS have been performed at intervals shorter than 4 weeks.lld:pubmed
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pubmed-article:12601106pubmed:articleTitleMRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals.lld:pubmed
pubmed-article:12601106pubmed:affiliationDepartment of Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.lld:pubmed
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