| pubmed-article:12565982 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0001792 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C1516985 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0024883 | lld:lifeskim |
| pubmed-article:12565982 | lifeskim:mentions | umls-concept:C0039286 | lld:lifeskim |
| pubmed-article:12565982 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12565982 | pubmed:dateCreated | 2003-2-4 | lld:pubmed |
| pubmed-article:12565982 | pubmed:abstractText | For treatment of early breast cancer in older women, little evidence is available from randomised trials. We conducted a randomised trial comparing modified radical mastectomy (MRM) with tamoxifen (TAM) as the sole initial therapy in 164 patients aged >/=70 years with operable breast cancer. 82 were treated by MRM and 82 with TAM. Survival curves were estimated using the Kaplan-Meier method: multivariate analyses were performed using the Cox's proportional hazards model. Endpoints included survival, time to first relapse or progression, loco-regional progression, time to distant progression and progression-free survival. After a median follow-up of approximately 10 years, there was a significantly decreased time to progression in the TAM only group (logrank P<0.0001) and significantly shorter time to local progression within the TAM group (logrank P<0.0001). Overall survival of the two groups was similar. The results indicate that tamoxifen alone leads to an unacceptably high rate of local progression or relapse. | lld:pubmed |
| pubmed-article:12565982 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12565982 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12565982 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565982 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12565982 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:12565982 | pubmed:issn | 0959-8049 | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:LegrandCC | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:BernerJJ | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:FentimanI SIS | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:ParidaensRR | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:WildiersJJ | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:TherassePP | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:NagadowskaMM | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:de KeizerGG | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:RutgersEE | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:Van GeelAA | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:EORTC | lld:pubmed |
| pubmed-article:12565982 | pubmed:author | pubmed-author:ChristiaensM-... | lld:pubmed |
| pubmed-article:12565982 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12565982 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:12565982 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12565982 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12565982 | pubmed:pagination | 309-16 | lld:pubmed |
| pubmed-article:12565982 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:meshHeading | pubmed-meshheading:12565982... | lld:pubmed |
| pubmed-article:12565982 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12565982 | pubmed:articleTitle | Treatment of operable breast cancer in the elderly: a randomised clinical trial EORTC 10851 comparing tamoxifen alone with modified radical mastectomy. | lld:pubmed |
| pubmed-article:12565982 | pubmed:affiliation | Hedley Atkins Breast Unit, Guy's Hospital, SE1 9RT, London, UK. ian.fentiman@cancer.org.uk | lld:pubmed |
| pubmed-article:12565982 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12565982 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:12565982 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12565982 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12565982 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
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