| pubmed-article:12565981 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0001792 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C1516985 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0024883 | lld:lifeskim |
| pubmed-article:12565981 | lifeskim:mentions | umls-concept:C0039286 | lld:lifeskim |
| pubmed-article:12565981 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12565981 | pubmed:dateCreated | 2003-2-4 | lld:pubmed |
| pubmed-article:12565981 | pubmed:abstractText | We have examined the outcome of older patients with operable breast cancer treated in a randomised trial by either standard surgery or less extensive surgery and tamoxifen. There were 236 participants aged >/=70 years, randomised to either modified radical mastectomy MRM (n=120) or wide local excision (WLE) and tamoxifen (T) 20 mg daily (n=116). Survival curves were estimated using the Kaplan-Meier method and multivariate analyses were performed using Cox's proportional hazards model. Endpoints were survival and time to first relapse or progression, loco-regional progression, time to distant progression and progression-free survival. No significant difference was seen in terms of progression-free survival, but there were significantly more loco-regional relapses in the WLE+T group. In contrast, there were more distant metastases in the MRM group, but with a similar overall survival in both groups. The results of this trial give cautious support for the use of WLE+T for selected older women. | lld:pubmed |
| pubmed-article:12565981 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12565981 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12565981 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12565981 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12565981 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:12565981 | pubmed:issn | 0959-8049 | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:LegrandCC | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:MargreiterRR | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:FentimanI SIS | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:ChaudaryM AMA | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:TherassePP | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:KarydasII | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:van ZijlJJ | lld:pubmed |
| pubmed-article:12565981 | pubmed:author | pubmed-author:EORTC | lld:pubmed |
| pubmed-article:12565981 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12565981 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:12565981 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12565981 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12565981 | pubmed:pagination | 300-8 | lld:pubmed |
| pubmed-article:12565981 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
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| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
| pubmed-article:12565981 | pubmed:meshHeading | pubmed-meshheading:12565981... | lld:pubmed |
| pubmed-article:12565981 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12565981 | pubmed:articleTitle | Treatment of operable breast cancer in the elderly: a randomised clinical trial EORTC 10850 comparing modified radical mastectomy with tumorectomy plus tamoxifen. | lld:pubmed |
| pubmed-article:12565981 | pubmed:affiliation | Hedley Atkins Breast Unit, Guy's Hospital, SE1 9RT, London, UK. ian.fentiman@cancer.org.uk | lld:pubmed |
| pubmed-article:12565981 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12565981 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:12565981 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12565981 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12565981 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12565981 | lld:pubmed |
