| pubmed-article:125444 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:125444 | lifeskim:mentions | umls-concept:C0035983 | lld:lifeskim |
| pubmed-article:125444 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:125444 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:125444 | lifeskim:mentions | umls-concept:C1325522 | lld:lifeskim |
| pubmed-article:125444 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:125444 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:125444 | pubmed:dateCreated | 1975-11-5 | lld:pubmed |
| pubmed-article:125444 | pubmed:abstractText | The effects of ryanodine on calcium transport were examined on a microsomal fraction isolated from guinea pig atrial muscle by sucrose density ultracentrifugation. The Ca+2 binding capacity of the fraction was sufficient to account for relaxation and was unaltered by the addition of 5x10(-5)M ryanodine. Exposure of the sarcoplasmic reticulum (SR) to concentrations of ryanodine which produce negative inotropy significantly reduced ATP-dependent calcium transport which was associated with a significant increase in the Ca+2 activated ATPase activity. The effect of ryanodine was to reduce the Ca/P ratio by 50%. These results suggest that the negative inotropic effect of ryanodine in guinea pig atrium is associated with the uncoupling of Ca+2 transport from ATP hydrolysis. | lld:pubmed |
| pubmed-article:125444 | pubmed:language | eng | lld:pubmed |
| pubmed-article:125444 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:125444 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:125444 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:125444 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:125444 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:125444 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:125444 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:125444 | pubmed:month | May | lld:pubmed |
| pubmed-article:125444 | pubmed:issn | 0034-5164 | lld:pubmed |
| pubmed-article:125444 | pubmed:author | pubmed-author:FrankMM | lld:pubmed |
| pubmed-article:125444 | pubmed:author | pubmed-author:SleatorW WWW | lld:pubmed |
| pubmed-article:125444 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:125444 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:125444 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:125444 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:125444 | pubmed:pagination | 65-72 | lld:pubmed |
| pubmed-article:125444 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-A... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-M... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-C... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-G... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-A... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-A... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-M... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-C... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-M... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-H... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-S... | lld:pubmed |
| pubmed-article:125444 | pubmed:meshHeading | pubmed-meshheading:125444-R... | lld:pubmed |
| pubmed-article:125444 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:125444 | pubmed:articleTitle | Effects of ryanodine on a myocardial membrane vesicular fraction. | lld:pubmed |
| pubmed-article:125444 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:125444 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:125444 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:125444 | lld:pubmed |
