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pubmed-article:12537215pubmed:abstractTextIn failing hearts, homeostatic mechanisms contrive to maximize stroke work and maintain normal arterial blood pressure at the expense of energetic efficiency. In contrast dobutamine reestablishes maximal mechanical efficiency by promoting energetically optimal loading conditions. However, dobutamine also wastefully increases nonmechanical oxygen consumption. We investigated whether direct mechanical cardiac compression would reestablish maximal mechanical efficiency without the oxygen-wasting effect.lld:pubmed
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pubmed-article:12537215pubmed:authorpubmed-author:ShirotaKazuak...lld:pubmed
pubmed-article:12537215pubmed:authorpubmed-author:HuangYifeiYlld:pubmed
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pubmed-article:12537215pubmed:authorpubmed-author:MartinDonaldDlld:pubmed
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pubmed-article:12537215pubmed:volume75lld:pubmed
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pubmed-article:12537215pubmed:pagination190-6lld:pubmed
pubmed-article:12537215pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:12537215pubmed:year2003lld:pubmed
pubmed-article:12537215pubmed:articleTitleDirect compression of the failing heart reestablishes maximal mechanical efficiency.lld:pubmed
pubmed-article:12537215pubmed:affiliationCooperative Research Centre for Cardiac Technology, Department of Cardiology, Royal North Shore Hospital, St. Leonards, Sydney, Australia.lld:pubmed
pubmed-article:12537215pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12537215pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed