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pubmed-article:12525924pubmed:abstractTextThe genodiversity of Staphylococcus aureus isolates from the Nottingham region of the United Kingdom was compared with isolates from the Freiburg region of Germany. The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) isolates was higher in Nottingham than in Freiburg. In patients from Nottingham hospitals, 80% of MRSA isolates were classical epidemic MRSA-15, but genotypic variants of epidemic MRSA-15 comprised 72% of isolates from Nottingham community-based patients. In contrast, MRSA isolates from Freiburg showed greater diversity, but 47% and 23% of isolates, respectively, belonged to two predominant MRSA genotypes found in isolates from both hospitalised and community-based patients. The results suggest that genodiversity becomes increasingly more confined in settings with a higher frequency and longer duration of MRSA prevalence.lld:pubmed
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pubmed-article:12525924pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:12525924pubmed:articleTitleDiversity of Staphylococcus aureus strains isolated from two European regions with different prevalences of methicillin resistance.lld:pubmed
pubmed-article:12525924pubmed:affiliationInstitute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany. djonas@IUK3.UKL.uni-Freiburg.delld:pubmed
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