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pubmed-article:12500242pubmed:abstractTextPatients with short bowel syndrome (SBS) have steatorrhea, in part because of bile acid malabsorption that causes decreased bile acid secretion into the duodenum and consequent fat maldigestion. In SBS patients with colon in continuity, luminal calcium forms calcium fatty acid soaps rather than precipitating as insoluble calcium oxalate. Soluble oxalate is hyperabsorbed by the colon leading to hyperoxaluria and an increased risk for renal calcium oxalate stones and deposits. The authors hypothesized that oral ingestion of conjugated bile acids would increase fat absorption and thereby decrease calcium fatty acid soap formation and oxalate hyperabsorption.lld:pubmed
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pubmed-article:12500242pubmed:copyrightInfoCopyright 2003 by the National Kidney Foundation, Inc.lld:pubmed
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pubmed-article:12500242pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:12500242pubmed:articleTitleConjugated bile acid replacement therapy reduces urinary oxalate excretion in short bowel syndrome.lld:pubmed
pubmed-article:12500242pubmed:affiliationDepartment of Internal Medicine, Baylor University Medical Center, Dallas, TX 75246, USA. m.emmett@baylorhealth.edulld:pubmed
pubmed-article:12500242pubmed:publicationTypeJournal Articlelld:pubmed
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