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pubmed-article:12479658pubmed:abstractTextCurrent guidelines provide little practical information on the clinical characteristics of bipolar I patients who are likely to benefit from the combination of a mood stabilizer and an antidepressant. Rather, guidelines simply state that an adjunctive antidepressant is recommended in cases of 'severe' depression. Our objective was to evaluate the clinical and demographic differences between patients who remitted on a mood stabilizer alone and patients who subsequently required an adjunctive antidepressant to achieve stabilization.lld:pubmed
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pubmed-article:12479658pubmed:articleTitleClinical indicators for the use of antidepressants in the treatment of bipolar I depression.lld:pubmed
pubmed-article:12479658pubmed:affiliationDepartment of Psychiatry University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA.lld:pubmed
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