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pubmed-article:12458332pubmed:dateCreated2002-11-29lld:pubmed
pubmed-article:12458332pubmed:abstractTextThe aim of this study was to evaluate practice usefulness of whole body positron emission tomography (PET) with 18F-fluoro-2-deoxyglucose (FDG) to detect recurrent ovarian cancer based on asymptomatically elevated tumor marker (CA-125) serum levels. Whole-body FDG-PET was performed in 28 patients with suspected recurrent ovarian cancers and asymptomatically increased serum levels of tumor marker (CA-125 antigen) but negative or equivocal other imaging modality results. All of these 28 asymptomatic patients had serum levels of CA-125 antigen >35 U/ml. The final diagnosis of recurrent ovarian cancer was established by operation/biopsy histopathological findings or clinical follow-up longer than 1 year by additional morphologic imaging techniques. Among the 28 patients, the final diagnoses of recurrent ovarian cancers and benign lesions were established in 20 and 8 patients, respectively. FDG-PET accurately diagnosed recurrent ovarian cancers in 19 patients and benign lesions in 7 patients. When asymptomatically elevated serum levels of CA-125 antigen, the diagnostic sensitivity, specificity, and accuracy of FDG-PET to detect recurrent ovarian cancers were 95.0%, 87.5%, and 92.9%, respectively. FDG-PET is a useful technique to detect recurrent ovarian cancers for patients suspected of recurrent ovarian cancers due to asymptomatically elevated serum levels of CA-125 antigen.lld:pubmed
pubmed-article:12458332pubmed:languageenglld:pubmed
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pubmed-article:12458332pubmed:statusMEDLINElld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:LinC CCClld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:ChangW CWClld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:ShenY YYYlld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:KaoC HCHlld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:YeoR GRGlld:pubmed
pubmed-article:12458332pubmed:authorpubmed-author:HungY CYClld:pubmed
pubmed-article:12458332pubmed:ownerNLMlld:pubmed
pubmed-article:12458332pubmed:authorsCompleteYlld:pubmed
pubmed-article:12458332pubmed:pagination329-33lld:pubmed
pubmed-article:12458332pubmed:dateRevised2004-11-17lld:pubmed
pubmed-article:12458332pubmed:articleTitleUsefulness of whole body positron emission tomography (PET) with 18F-fluoro-2-deoxyglucose (FDG) to detect recurrent ovarian cancer based on asymptomatically elevated serum levels of tumor marker.lld:pubmed
pubmed-article:12458332pubmed:affiliationDepartment of Obstetrics & Gynecology; China Medical College Hospital, Taichung, Taiwan. d10040@www.cmch.org.twlld:pubmed
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