A better understanding of inflammatory processes in endothelial cells (ECs) might reveal new ways of controlling inflammation and graft rejection. This study investigates EC genes regulated in response to human tumor necrosis factor (TNF)-alpha and xenogeneic natural antibodies (XNAs) that contribute to endothelial activation during transplantation.
INSERM U437 Immunointervention en Allo-Xénotransplantation and Institut de Transplantation et de Recherche en Transplantation, C.H.U. Hôtel-Dieu, Nantes Cedex, France.
