The age-standardized mortality rate for hepatocellular carcinoma is increasing in several countries. However, in England and Wales we previously reported an increase in mortality rates from intrahepatic cholangiocarcinoma. Trends in cholangiocarcinoma in most other industrialized countries are unknown. To further study trends in hepatobiliary and pancreatic tumours, we analysed mortality data from the United States, Japan, Australia and Europe.
Liver Unit, Department of Medicine A, Faculty of Medicine, 10th Floor, QEQM Wing, Imperial College School of Medicine, St Mary's Hospital, South Wharf Street, London W2 1PG, UK. shahid.khan@ic.ac.uk