Linked Life Data

12438291

Source:http://linkedlifedata.com/resource/pubmed/id/12438291

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pubmed-article:12438291pubmed:dateCreated2002-11-19lld:pubmed
pubmed-article:12438291pubmed:abstractTextThe endothelin (ET-1) system is activated in chronic heart failure (CHF). Whether, what type, and what degree of selective ET blockade is clinically beneficial is unknown. We investigated hemodynamic and neurohumoral effects of 3 weeks of treatment with various dosages of the orally available ET(A) antagonist darusentan in addition to modern standard therapy in patients with CHF.lld:pubmed
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pubmed-article:12438291pubmed:pagination2666-72lld:pubmed
pubmed-article:12438291pubmed:dateRevised2007-11-15lld:pubmed
pubmed-article:12438291pubmed:articleTitleHemodynamic and neurohumoral effects of selective endothelin A (ET(A)) receptor blockade in chronic heart failure: the Heart Failure ET(A) Receptor Blockade Trial (HEAT).lld:pubmed
pubmed-article:12438291pubmed:affiliationCardiovascular Center, Cardiology, University Hospital, Zürich, Switzerland. cardiotfl@gmx.chlld:pubmed
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