| pubmed-article:12431062 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C0002520 | lld:lifeskim |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C1417964 | lld:lifeskim |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C1373041 | lld:lifeskim |
| pubmed-article:12431062 | lifeskim:mentions | umls-concept:C0231491 | lld:lifeskim |
| pubmed-article:12431062 | pubmed:dateCreated | 2002-11-14 | lld:pubmed |
| pubmed-article:12431062 | pubmed:abstractText | Azacycloalkane turn mimics 6-9 were used to explore the relationship between conformation and biological activity of peptide ligands to the opioid receptor-like (ORL1) receptor. Three azabicyclo[x.y.0]alkane amino acids and a 5-tBuPro type VI beta-turn mimic were introduced into peptides 10-13 by solid-phase synthesis on MBHA resin. Biological examination of peptides 10-13 showed two new antagonists (10 and 12) exhibiting increased selectivity for the ORL1 receptor. | lld:pubmed |
| pubmed-article:12431062 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12431062 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12431062 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:TourwéDirkD | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:KiefferBrigit... | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:SimoninFrédér... | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:HalabLilianeL | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:LubellWilliam... | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:DarulaZsuzsan... | lld:pubmed |
| pubmed-article:12431062 | pubmed:author | pubmed-author:BeckerJérôme... | lld:pubmed |
| pubmed-article:12431062 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12431062 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12431062 | pubmed:pagination | 5353-7 | lld:pubmed |
| pubmed-article:12431062 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12431062 | pubmed:articleTitle | Probing opioid receptor interactions with azacycloalkane amino acids. Synthesis of a potent and selective ORL1 antagonist. | lld:pubmed |
| pubmed-article:12431062 | pubmed:affiliation | Département de Chimie, Université de Montréal, C. P. 6128, Succursale Centre Ville, Montréal, Québec, Canada H3C 3J7. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:12431062 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12431062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12431062 | lld:pubmed |
