pubmed-article:12408489 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0027361 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0021968 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C2242456 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0018517 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0205266 | lld:lifeskim |
pubmed-article:12408489 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
pubmed-article:12408489 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:12408489 | pubmed:dateCreated | 2002-10-31 | lld:pubmed |
pubmed-article:12408489 | pubmed:abstractText | A joint project between the Human Monitoring Laboratory (HML) and the Ottawa Hospital has measured the retention of 131I in patients who have received the radioiodine diagnostically. Thirty-nine subjects with intact thyroid glands and nine athyreotic subjects were measured in the HML's whole-body/thyroid counter to determine the retention of 131I following its medical administration. The average biological half-life of 131I in 26 euthyroid subjects was found to be 66.1+/-6.3 days which may he statistically significantly lower than the ICRP recommended value of 80 days. Nine hyperthyroid patients had a mean biological half-life of 38.2+/-8.6 days and in three hypothyroid patients the corresponding value was 29.3+/-8.8 days. Thyroid 131I uptake was measured in a conventional clinical fashion at the Ottawa Hospital Civic campus 24 h after oral administration of the radioiodine using a collimated thick sodium iodide detector placed over the neck anteriorly. Measured values were 10.144+/-0.009, 0.314+/-0.035 and 0.045+/-0.010 of the administered dose in euthyroid, hyperthyroid and hypothyroid patients respectively. The euthyroid range at the hospital is 0.06 - 0.22. Uptake was significantly lower for the euthyroid group than the ICRP value of 0.3. The radioiodine retention in athyreotic subjects followed a two compartment model with biological half-lives of 1.0+/-1.2 days and 18.4+/-1.1 days. | lld:pubmed |
pubmed-article:12408489 | pubmed:language | eng | lld:pubmed |
pubmed-article:12408489 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12408489 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12408489 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12408489 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12408489 | pubmed:issn | 0144-8420 | lld:pubmed |
pubmed-article:12408489 | pubmed:author | pubmed-author:ChamberlainM... | lld:pubmed |
pubmed-article:12408489 | pubmed:author | pubmed-author:KramerG HGH | lld:pubmed |
pubmed-article:12408489 | pubmed:author | pubmed-author:HauckB MBM | lld:pubmed |
pubmed-article:12408489 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12408489 | pubmed:volume | 102 | lld:pubmed |
pubmed-article:12408489 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12408489 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12408489 | pubmed:pagination | 129-35 | lld:pubmed |
pubmed-article:12408489 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:12408489 | pubmed:year | 2002 | lld:pubmed |
pubmed-article:12408489 | pubmed:articleTitle | Biological half-life of iodine in adults with intact thyroid function and in athyreotic persons. | lld:pubmed |
pubmed-article:12408489 | pubmed:affiliation | Human Monitoring Laboratory, Radiation Protection Bureau, Ottawa, Ontario, Canada. Gary_H_Kramer@hc-sc.gc.ca | lld:pubmed |
pubmed-article:12408489 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12408489 | pubmed:publicationType | Comparative Study | lld:pubmed |