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pubmed-article:12393102pubmed:abstractTextThe morphogenetic process underlying the remodelling of the embryonic mammalian pharyngeal arch artery system is unknown. Within this process, the right sixth, carotid ducts and the distal part of the dorsal aorta (right alpha-segment) regress. In order to unravel the underlying mechanism we studied the role of apoptosis in the normal regression of pharyngeal arch artery segments and in a mouse model that develops aortic arch malformations.lld:pubmed
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pubmed-article:12393102pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:12393102pubmed:articleTitleAltered apoptosis pattern during pharyngeal arch artery remodelling is associated with aortic arch malformations in Tgfbeta2 knock-out mice.lld:pubmed
pubmed-article:12393102pubmed:affiliationDepartment of Anatomy and Embryology, Leiden University Medical Centre, P.O. Box 9602, 2300 RC, Leiden, The Netherlands.lld:pubmed
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pubmed-article:12393102pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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