pubmed-article:12391492 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12391492 | lifeskim:mentions | umls-concept:C0030567 | lld:lifeskim |
pubmed-article:12391492 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:12391492 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
pubmed-article:12391492 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:12391492 | pubmed:dateCreated | 2002-10-22 | lld:pubmed |
pubmed-article:12391492 | pubmed:abstractText | We tested whether dispersible L-dopa has acute effects on event-related desynchronization (ERD) of the mu rhythm in patients with idiopathic Parkinson's disease (IPD). ERD to voluntary movement is delayed in akinetic IPD patients and improves after chronic L-dopa treatment. We evaluated ERD to self-paced finger movement in 14 IPD patients (before and 30-40 min after oral administration of dispersible L-dopa) and in 10 normal subjects. Sensorimotor ERD onset contralateral to movement was significantly delayed in IPD patients compared to normal subjects. This abnormality was no longer significant after L-dopa treatment. We conclude that a single dose of dispersible L-dopa can improve not only motor performance in IPD patients but also the timing of cortical activation of sensorimotor areas during motor programming. | lld:pubmed |
pubmed-article:12391492 | pubmed:language | eng | lld:pubmed |
pubmed-article:12391492 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12391492 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12391492 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12391492 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12391492 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12391492 | pubmed:month | Sep | lld:pubmed |
pubmed-article:12391492 | pubmed:issn | 1590-1874 | lld:pubmed |
pubmed-article:12391492 | pubmed:author | pubmed-author:MagnaniGG | lld:pubmed |
pubmed-article:12391492 | pubmed:author | pubmed-author:ComiGG | lld:pubmed |
pubmed-article:12391492 | pubmed:author | pubmed-author:CursiMM | lld:pubmed |
pubmed-article:12391492 | pubmed:author | pubmed-author:VolontéM AMA | lld:pubmed |
pubmed-article:12391492 | pubmed:author | pubmed-author:LeocaniLL | lld:pubmed |
pubmed-article:12391492 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12391492 | pubmed:volume | 23 | lld:pubmed |
pubmed-article:12391492 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12391492 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12391492 | pubmed:pagination | 91-7 | lld:pubmed |
pubmed-article:12391492 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:12391492 | pubmed:year | 2002 | lld:pubmed |
pubmed-article:12391492 | pubmed:articleTitle | Acute effects of L-dopa on event-related desynchronization in Parkinson's disease. | lld:pubmed |
pubmed-article:12391492 | pubmed:affiliation | Department of Clinical Neurophysiology, San Raffaele Scientific Institute, Milan, Italy. | lld:pubmed |
pubmed-article:12391492 | pubmed:publicationType | Journal Article | lld:pubmed |