pubmed-article:1237265 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0003308 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0032473 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0282563 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
pubmed-article:1237265 | lifeskim:mentions | umls-concept:C0054584 | lld:lifeskim |
pubmed-article:1237265 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:1237265 | pubmed:dateCreated | 1976-1-2 | lld:pubmed |
pubmed-article:1237265 | pubmed:abstractText | The candihexin complex produced by a natural mutant of Streptomyces viridoflavus has been resolved into eight components. At least six of them, having hexaene chromophores, can be separated directly by thin-layer chromatography. The four major components, candihexins A, B, E, and F, account for about 90% of the total complex. They have been isolated and purified to homogeneity. All the major components were found to have macrolide lactone rings with all-trans hexaene chromophores. Candihexins A and B have compositions and molecular weights similar to candidin, the heptaene polyene macrolide produced by the parent S. viridoflavus, whereas candihexins E and F show smaller molecular weights and rather different elementary compositions. Candihexins A and B yield the amino sugar mycosamine upon hydrolysis, but no sugar was found in hydrolysates of candihexins E and F. Candihexins A and B have high antifungal activity against yeasts and filamentous fungi. The amino sugar-lacking candihexins E and F show no antifungal activity at levels of 100 mug/ml. | lld:pubmed |
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pubmed-article:1237265 | pubmed:language | eng | lld:pubmed |
pubmed-article:1237265 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1237265 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1237265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1237265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1237265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1237265 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1237265 | pubmed:month | Aug | lld:pubmed |
pubmed-article:1237265 | pubmed:issn | 0066-4804 | lld:pubmed |
pubmed-article:1237265 | pubmed:author | pubmed-author:MartinJ FJF | lld:pubmed |
pubmed-article:1237265 | pubmed:author | pubmed-author:McDanielL ELE | lld:pubmed |
pubmed-article:1237265 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1237265 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:1237265 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1237265 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1237265 | pubmed:pagination | 200-8 | lld:pubmed |
pubmed-article:1237265 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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pubmed-article:1237265 | pubmed:meshHeading | pubmed-meshheading:1237265-... | lld:pubmed |
pubmed-article:1237265 | pubmed:year | 1975 | lld:pubmed |
pubmed-article:1237265 | pubmed:articleTitle | Candihexin polyene macrolide complex: physicochemical characterization and antifungal activities of the single components. | lld:pubmed |
pubmed-article:1237265 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1237265 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |