| pubmed-article:12362448 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C0991850 | lld:lifeskim |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C1547276 | lld:lifeskim |
| pubmed-article:12362448 | lifeskim:mentions | umls-concept:C0050156 | lld:lifeskim |
| pubmed-article:12362448 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:12362448 | pubmed:dateCreated | 2002-10-4 | lld:pubmed |
| pubmed-article:12362448 | pubmed:abstractText | Conjugated linoleic acid (CLA) is a fatty acid with numerous putative health benefits and is a natural component of ruminant-derived food products. An intermediate in rumen biohydrogenation is cis-9, trans-11 CLA, the major CLA isomer in milk fat. However, the major source of cis-9, trans-11 CLA in milk is endogenous synthesis by delta 9-desaturase conversion of trans-11 C18:1, another rumen biohydrogenation intermediate. The desaturase indices serve as a proxy for delta 9-desaturase activity and are calculated from the ratios of fatty acid pairs that represent product/substrate for this enzyme. This study analyzed individual animal variation in milk fat content of cis-9, trans-11 CLA and in desaturase indices in milk fat. Thirty lactating Holstein cows were allocated to one of three treatment groups: one received a standard total mixed ration, one received a diet that produced an elevated milk fat content of CLA, and a third treatment group was alternated between these diets at 3-wk intervals over the 12-wk study. There was a two- to threefold variation among individuals on the same diet for both milk fat content of CLA and desaturase indices in milk fat. This hierarchy was maintained to a large extent over the 12-wk study even in the variable treatment group that alternated between the two diets. Within the variable diet treatment, some animals consistently had a substantial response in milk fat content of CLA to dietary shifts, whereas other cows had little or no response. We conclude that while diet is a major determinant of the CLA content in milk fat, individual animal differences also have a substantial effect. The variation among individuals includes differences related to both rumen biohydrogenation and delta 9-desaturase activity in the mammary gland. | lld:pubmed |
| pubmed-article:12362448 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12362448 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12362448 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12362448 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12362448 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12362448 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12362448 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12362448 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12362448 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:12362448 | pubmed:issn | 0022-0302 | lld:pubmed |
| pubmed-article:12362448 | pubmed:author | pubmed-author:BaumanD EDE | lld:pubmed |
| pubmed-article:12362448 | pubmed:author | pubmed-author:KelseyJ AJA | lld:pubmed |
| pubmed-article:12362448 | pubmed:author | pubmed-author:PetersonD GDG | lld:pubmed |
| pubmed-article:12362448 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12362448 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:12362448 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12362448 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12362448 | pubmed:pagination | 2164-72 | lld:pubmed |
| pubmed-article:12362448 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:meshHeading | pubmed-meshheading:12362448... | lld:pubmed |
| pubmed-article:12362448 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12362448 | pubmed:articleTitle | Analysis of variation in cis-9, trans-11 conjugated linoleic acid (CLA) in milk fat of dairy cows. | lld:pubmed |
| pubmed-article:12362448 | pubmed:affiliation | Department of Animal Science, Cornell University, Ithaca, NY 14853, USA. | lld:pubmed |
| pubmed-article:12362448 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12362448 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12362448 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12362448 | lld:pubmed |
